Aloe Vera’s Anti-Inflammatory Effects

The U. S. National Library of Medicine in their Abstract on Aloe Vera for Tissue Engineering reports the following as regards to Aloe Vera’s effect on inflammation:

“Aloe has been described as having anti-inflammatory effects, wound healing properties, radiation damage repair benefits, antibacterial, antiviral, antifungal, antidiabetic, and antineoplastic activities, hematopoietic stimulation, and antioxidant effects [,].

“The polysaccharides are responsible for the majority of the biological activities observed from the use of the aloe vera plant []. However, the biological activities of aloe vera result from a synergistic action of a variety of compounds []. The polysaccharides consist of linear chains of glucose and mannose molecules. The major polysaccharides include cellulose, hemicellulose, glucomannans, mannose derivative, and acetylated compounds. Acemannan and glucomannan are considered the two main functional components of aloe vera. Acemannan is composed of a long chain of acetylated mannose, i.e., β-(1,4)-linked acetylated mannose with molecular weights ranging from 30 to 40 kDa or greater [,].

“The anti-inflammatory effect of aloe is a result of mannose-6-phosphate and acemannan []. Glucomannan and acemannan were proved to accelerate tissue regeneration, activate macrophages, stimulate the immune system, and have antibacterial and antiviral effects [].

“These aloe vera constituents are thought to reduce inflammation caused by an increase in prostaglandin synthesis and an increase in the infiltration of leukocytes [,]. Acemannan also plays an important role in cellular metabolism by regulating the flow of nutrients and wastes.

” The anti-inflammatory effects of the plant are also a result of the inhibition of enzymes involved in inflammation [].”


This is good news for those who have included Aloe Apex into their daily regimen! If you haven’t yet added Aloe Apex to your daily regimen you can check out the benefits here.


  1. Sheila on November 13, 2017 at 9:30 am

    I was wondering if this would help me? I have burning nerve pain on the left side of my groin down my upper thigh. My doctor said she thinks I have a pinched nerve. Thanks

  2. Duane Hughes on November 13, 2017 at 5:23 pm


    Aloe Apex has many benefits, however it is not formulated for pain or a pinched nerve. There are anti-inflammation qualities in the product which may provide some relief from inflammation associated with the nerve issue.

    Best of health

  3. Ruth Beard on August 16, 2019 at 7:18 am

    Hi Duane,

    Thank you for your presentation on God TV with Doug regarding DNA etc. Just wondering, Im on Chemotherapy and wondering if I can take Aloe Vera as well.

    or and what else would you recommend for me.

    Looking forward to hear from you soon.


  4. Duane on August 16, 2019 at 4:26 pm


    Thanks you for your inquiry. Yes, the Aloe Apex should help with the Chemo, however the best results for people that are taking Chemo has been with our Alive Again functional beverage. I would recommend you take both to give you the maximum benefit of the Aloe Vera and the energy properties of the Alive Again.

    Blessing to you and bet of health,

  5. Sharon Hughes on November 28, 2019 at 1:21 pm

    Thank you for your feedback, Ruth. Our Alive Again drink has helped many while they are on chemotherapy, by their own testimony. There are no interactions between chemo and our products, but, of course, you want to follow your doctor’s recommendations.

  6. Liz on December 5, 2019 at 7:54 am

    Interested in learning more about the product for digestion/elimination

  7. Sharon Hughes on December 6, 2019 at 2:44 pm

    Hi Liz, please explore more resources of information on our website, both on the blog and under research, and also the testimonies from customers.

  8. Sharon Hughes on March 20, 2021 at 2:03 pm

    Hi Liz, please see the tab on the website under Products. You may also find it helpful to listen to the testimonials as well. All the best in health to you.